Results 21 to 30 of about 50,878 (260)

Numerical investigation of pile foundation systems employing an enhanced embedded finite element

open access: yesFrontiers in Built Environment
The design of large-scale pile foundation systems is routinely assisted by finite element simulations. To a large extent, both the modeling and the computational effort of such analyses are governed by the adopted pile modeling technique. The traditional
Andreas-Nizar Granitzer   +5 more
doaj   +1 more source

Seismic Performance Evaluation of a Fully Integral Concrete Bridge with End-Restraining Abutments

open access: yesAdvances in Civil Engineering, 2019
A fully integral bridge that is restrained at both ends by the abutments has been proposed to form a monolithic rigid frame structure. Thus, the feasible horizontal force effect due to an earthquake or vehicle braking is mainly prevented by the end ...
Byung H. Choi   +4 more
doaj   +1 more source

Closure Scheme Analysis of 3 × 70 m Bearingless Integral Rigid Frame Bridge of Fuzhou Xiamen High-Speed Railway

open access: yesAdvances in Civil Engineering, 2023
The hydrodynamic problems associated with the construction of the sea-crossing bridge were proposed. The deep-water approach bridge on both sides of the main bridge of Fuzhou Xiamen high-speed railway adopts the bearingless prestressed concrete integral ...
Fangwen Weng, Xiangui Li
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Forms and Aesthetics of Bridges

open access: yesEngineering, 2018
The objective of a bridge design is to produce a safe bridge that is elegant and satisfies all functionality requirements, at a cost that is acceptable to the owner.
Man-Chung Tang
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Experimental verification of numerical model of integral bridge

open access: yesBudownictwo i Architektura, 2014
The paper presents the results of analyses of displacements for a real reinforced concrete integral bridge. The research consisted of the measurement of vertical displacement in the middle of the span and lateral displacement of the abutment.
Jakub Jarosz
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Integral bridge abutments in response to seasonal temperature changes: State of knowledge and recent advances

open access: yesFrontiers in Built Environment, 2022
Expansion and contraction of integral abutment bridges due to temperature changes force integral bridge abutments (IBAs) to move toward and away from the backfill, thus increasing horizontal earth pressures behind the abutments and inducing bending ...
Hao Liu, Jie Han, Robert L. Parsons
doaj   +1 more source

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