Results 21 to 30 of about 21,307 (263)

NON-LINEAR ANALYSIS OF AN INTEGRAL BRIDGE [PDF]

JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT, 2010
This study describes the implementation of a 2‐D finite element model of an integral abutment bridge (IAB) system which explicitly incorporates the nonlinear soil response. The superstructure members have been represented by means of three‐node isoparametric beam elements with three degrees of freedom per node.
Noorzaei, Jamaloddin, Abdulrazeg, Aeid. A., Jaafar, Mohd Saleh, Kohnehpooshi, Omid   +3 more
openaire   +2 more sources

Transition Effects in Bridge Structures and Their Possible Reduction Using Recycled Materials

Applied Sciences
This article serves as a review of the current challenges in bridge engineering, specifically addressing the transition effect and the utilization of recycled materials.
Mariusz Spyrowski, Krzysztof Adam Ostrowski, Kazimierz Furtak   +2 more
doaj   +1 more source

Local scour around complex pier groups and combined piles at semi-integral bridge

Journal of Hydrology and Hydromechanics, 2014
This research presents an experimental study on the scouring mechanism at semi-integral bridge piers. Based on laboratory experiments, this study focuses on the relationship between scour depth in complex pier groups and combined piles bridge and various
Akib Shatirah, Jahangirzadeh Afshin, Basser Hossein   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Multimode Adaptive Pushover Procedure for Seismic Assessment of Integral Bridges

Advances in Civil Engineering, 2013
This paper presents a new adaptive pushover procedure to account for the effect of higher modes in order to accurately estimate the seismic response of bridges.
Ehsan Mohtashami, Ahmad Shooshtari
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Assessment of Integral Abutment Retrofit Performance for Steel Bridges Subjected to Thermal Loading

Infrastructures
Integral abutment bridges (IABs) eliminate deck joints by rigidly connecting the superstructure to the abutments, reducing maintenance costs but introducing thermal restraint forces.
Jawad H. Gull, Sana Amir, Qasim Shaukat Khan   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source