Results 41 to 50 of about 402 (214)

Bridging the Integrity Gap

open access: yesASCILITE Publications
Academic integrity is a cornerstone of ethical scholarship and fair and credible higher education. However, many students – particularly those from underrepresented backgrounds (Bretag et al., 2019; Devlin et al., 2018; Dockery et al., 2016; Webb et al., 2024) such as international, low socio-economic, and regional, rural and remote cohorts - struggle ...
Suzanne E. Gilbey   +4 more
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Safety Identifying of Integral Abutment Bridges under Seismic and Thermal Loads

open access: yesThe Scientific World Journal, 2014
Integral abutment bridges (IABs) have many advantages over conventional bridges in terms of strength and maintenance cost. Due to the integrity of these structures uniform thermal and seismic loads are known important ones on the structure performance ...
Narges Easazadeh Far, Majid Barghian
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Torsional Behavior of Pylon Columns with Edge Cracks in Suspension Bridges Under Wind Loads

open access: yesBuildings
Cracks inevitably develop in the pylon structures of suspension bridges due to external forces such as wind loads. Cracks are a primary cause of torsional damage to the key supporting structures of suspension bridges.
Nan Liu   +7 more
doaj   +1 more source

Performance of Pier-to-Pier Cap Connections of Integral Bridges under Thermal and Seismic Loads

open access: yesAdvances in Civil Engineering, 2021
In general, most highway bridges are constructed using prestressed concrete or steel girders. Mechanical joints are provided at the end of each span, to allow for the expansion of the bridge deck due to shrinkage of concrete, thermal effects, and ...
Siva Avudaiappan   +5 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Life cycle assessment of the sustainability of bridges: methodology, literature review and knowledge gaps

open access: yesFrontiers in Built Environment
Analysing the entire project life cycle is a new trend in sustainability assessment in the construction sector. Research on sustainability issues in the construction sector started with issues related to buildings, while research for other structures ...
Ivana Milić, Jelena Bleiziffer
doaj   +1 more source

Home - About - Disclaimer - Privacy