Results 91 to 100 of about 4,987,876 (357)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

olution to a semilinear pseudoparabolic problem with integral conditions

open access: yesElectronic Journal of Differential Equations, 2006
In this article, we use the Rothe time-discretization method to prove the well-posedness of a mixed problem with integral conditions for a third order semilinear pseudoparabolic equation.
Abdelfatah Bouziani, Nabil Merazga
doaj  

Sturm‐Liouville problem for stationary differential operator with nonlocal integral boundary condition

open access: yesMathematical Modelling and Analysis, 2005
The Sturm‐Liouville problem with various types of nonlocal integral boundary conditions is considered in this paper. In the first part of paper we investigate Sturm‐Liouville problem with two cases of nonlocal integral boundary conditions.
S. Pečiulyte   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Positive solutions for a nonlocal multi-point boundary-value problem of fractional and second order

open access: yesElectronic Journal of Differential Equations, 2013
In this article we study the existence of positive solutions for the nonlocal multi-point boundary-value problem $$displaylines{ u''(t)+f(t, ^{c}D^{alpha}u(t))=0, quad alpha in(0, 1), ext{ a.e.
Ahmed M. A. El-Sayed   +1 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A distributional solution to a hyperbolic problem arising in population dynamics

open access: yesElectronic Journal of Differential Equations, 2007
We consider a generalization of the Lotka-McKendrick problem describing the dynamics of an age-structured population with time-dependent vital rates. The generalization consists in allowing the initial and the boundary conditions to be derivatives of the
Irina Kmit
doaj  

Existence of solutions of non-autonomous fractional differential equations with integral impulse condition

open access: yes, 2020
In this paper, we investigate the existence of solution of non-autonomous fractional differential equations with integral impulse condition by the measure of non-compactness (MNC), fixed point theorems, and k -set contraction.
Ashisha Kumar   +4 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Spectrum Curves for Sturm–Liouville Problem with Integral Boundary Condition

open access: yesMathematical Modelling and Analysis, 2015
We consider Sturm–Liouville problem with one integral type nonlocal boundary condition depending on three parameters γ (multiplier in nonlocal condition), ξ1, ξ2 ([ξ1, ξ2] is a domain of integration).
Agnė Skučaitė, Artūras Štikonas
doaj   +1 more source

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