Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Nonlocal problems for hyperbolic equations with degenerate integral conditions
Electronic Journal of Differential Equations, 2016 In this article, we consider a problem for hyperbolic equation with standard initial data and nonlocal condition. A distinct feature of this problem is that the nonlocal second kind integral condition degenerates and turns into a first kind.
Ludmila S. Pulkina
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
A boundary problem with integral gluing condition for a parabolic-hyperbolic equation involving the Caputo fractional derivative [PDF]
, 2013 Erkinjon Karimov, J. S. Akhatov
openalex +1 more source
, 2013 In this work, we study a telegraph integro-differential equation with a weighted integral condition. By means of the Galerkin method, we establish the existence and uniqueness of a generalized solution.MSC:35L05, 35L20, 35L99.
A. Guezane-Lakoud +2 more
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Inverse problem of a hyperbolic equation with an integral overdetermination condition
Electronic Journal of Differential Equations, 2016 In this article we study the inverse problem of a hyperbolic equation with an integral overdetermination condition. The existence, uniqueness and continuous dependence of the solution of the solution upon the data are established.
Taki-Eddine Oussaeif +1 more
doaj
Weak solvability of a hyperbolic integro-differential equation with integral condition
Electronic Journal of Qualitative Theory of Differential Equations, 2011 By using the method of semidiscretization in time also called the Rothe's method, we prove the existence, uniqueness of the weak solution and its continuous dependence upon data, for an hyperbolic integro-differential equation with initial, Neumann and ...
D. Belakroum, A. Guezane-Lakoud
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Problem with integral condition for a partial differential equation of the first order with respect to time [PDF]
, 2012 P. І. Kalenyuk +2 more
openalex +1 more source