Results 91 to 100 of about 679,276 (278)
Imperative role of adaptor proteins in macrophage toll-like receptor signaling pathways
Future Science OAMacrophages are integral part of the body's defense against pathogens and serve as vital regulators of inflammation. Adaptor molecules, featuring diverse domains, intricately orchestrate the recruitment and transmission of inflammatory responses through ...
Aurelia Rughetti +10 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 2001 We study initial-boundary value problem for an equation of composite type in 3-D multiply connected domain. This equation governs nonsteady inertial waves in rotating fluids.
Pavel A. Krutitskii
doaj +1 more source
ON RESIDUALLY INTEGRALLY CLOSED DOMAINS
Demonstratio Mathematica, 2003 Summary: A domain \(R\) is called residually integrally closed if \(R/p\) is an integrally closed domain for each prime ideal \(p\) of \(R\). We show that residually integrally closed domains satisfy some chain conditions on prime ideals. We give characterization of such domains in case they contain a field of characteristic 0.
Echi, Othman, Jarboui, Noômen
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A novel approach to nonlinear fractional volterra integral equations
Acta PolytechnicaNonlinear Fractional Volterra integral equations (FVIEs) of the first kind present challenges due to their intricate nature, combining fractional calculus and integral equations.
Mohammed Abdulshareef Hussein +1 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source