Results 51 to 60 of about 2,528,554 (279)
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The authors consider a Volterra integrodifferential equation of any order and of the second kind. They obtain exact and approximate solutions in the field of Mikusinski's operators \(F\), or, more precise, in a subspace \(F_c=\{f\in F\}\), where \(f\) is represented by a continuous function.
Takači, Arpad, Takači, Đurđica
openaire +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The primary focus of this paper is to thoroughly examine and analyze a class of a fractional quadratic integral equation via generalized fractional integral.
Alan Jalal Abdulqader +4 more
doaj +1 more source
Analysis of Two-Dimensional Heat Transfer Problem Using the Boundary Integral Equation
In this paper, we examine the problem of two-dimensional heat equations with certain initial and boundary conditions being considered. In a two-dimensional heat transport problem, the boundary integral equation technique was applied.
Nimona Ketema Kebeba, Gizaw Debito Haifo
doaj +1 more source
A Grassmann integral equation [PDF]
The present study introduces and investigates a new type of equation which is called Grassmann integral equation in analogy to integral equations studied in real analysis. A Grassmann integral equation is an equation which involves Grassmann (Berezin) integrations and which is to be obeyed by an unknown function over a (finite-dimensional) Grassmann ...
openaire +2 more sources
Markovian integral equations [PDF]
We analyze multidimensional Markovian integral equations that are formulated with a time-inhomogeneous progressive Markov process that has Borel measurable transition probabilities. In the case of a path-dependent diffusion process, the solutions to these integral equations lead to the concept of mild solutions to semilinear parabolic path-dependent ...
openaire +4 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

