Results 111 to 120 of about 108,480 (312)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Volterra integral and differential equations /
, 2005 Most mathematicians, engineers, and many other scientists are well-acquainted with theory and application of ordinary differential equations. This book seeks to present Volterra integral and functional differential equations in that same framwork ...
Burton, T. A.(Theodore Allen),
core
Positive solutions of a boundary value problem with integral boundary conditions [PDF]
, 2011 We consider boundary-value problems studied in a recent paper. We show that some existing theory developed by Webb and Infante applies to this problem and we use the known theory to show how to find improved estimates on parameters μ*, λ so ...
Webb, J.
core
Condition number estimates for combined potential boundary integral operators in acoustic scattering
, 2009 We study the classical combined field integral equation formulations for time-harmonic acoustic scattering by a sound soft bounded obstacle, namely the indirect formulation due to Brakhage-Werner/Leis/Panic, and the direct formulation associated with the
Chandler-Wilde, Simon Neil +9 more
core +1 more source
Conservative numerical methods for model kinetic equations [PDF]
, 2007 A new conservative discrete ordinate method for nonlinear model kinetic equations is proposed. The conservation property with respect to the collision integral is achieved by satisfying at the discrete level approximation conditions used in deriving the ...
Titarev, Vladimir A.
core +1 more source
Approximations of solutions to nonlinear Sobolev type evolution equations
Electronic Journal of Differential Equations, 2003 In the present work we study the approximations of solutions to a class of nonlinear Sobolev type evolution equations in a Hilbert space. These equations arise in the analysis of the partial neutral functional differential equations with unbounded delay.
Dhirendra Bahuguna, Reeta Shukla
doaj
Morse potential specific heat with applications: an integral equations theory based. [PDF]
BMC Chem, 2022 Al-Raeei M.
europepmc +1 more source
Integration of Stiff Equations [PDF]
Proceedings of the National Academy of Sciences, 1952 Curtiss, C. F., Hirschfelder, J. O.
openaire +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Efficient numerical methods for Volterra integral equations of Hammerstein type
, 2006 Volterra integral equations (VIEs) are the mathematical model of many evolutionary problems with memory arising from biology, chemistry, physics, engineering.
Del Prete, Ida
core