Results 91 to 100 of about 108,480 (312)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Hyperbolic harmonic functions and the associated integral equations

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science, 2015
In this paper we consider a class of integral equations associated with the invariant mean value property of hyperbolic harmonic functions. We have shown that nonconstant solutions of these integral equations are functions of unbounded variations and do ...
Das Namita, Lal Rajendra Prasad
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

On the approximation of linear integral equations

open access: yes, 1976
Integral equations form an important subject with applied mathematics due to their occurence in a variety of models of physical problems. The intent of this thesis is to present in a simple and concise manner the theory of integral equations in the ...
Ali, Agha I.
core  

Integral Equations Concepts and Solutions [PDF]

open access: yes, 2016
In this research I shall study general concepts of integral equations including classifications, some theorems that help in formulating the solutions analytically and numerically, with some applications of integral equations in applied and pure ...
Ahmed Abdalrhman Osman Mohamed
core  

Implicit integral equations with discontinuous nonlinearities [PDF]

open access: yes, 2002
In this paper we establish the existence ofa t least one solution for a class of implicit integral equations with possibly discontinuous nonlinearities, which includes the well known Chandrasekhar equation, among others. Our approach fully depends on
Candito P.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Approximate solution of second kind integral equations on infinite cylindrical surfaces

open access: yes, 1994
The paper considers second kind integral equations of the form (abbreviated)φφK+=g, in which S is an infinite cylindrical surface of arbitrary smooth cross-section.
Peplow, AT, Chandler-Wilde, SN
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

On asymptotic behaviour at infinity and the finite section for integral equations on the half-line

open access: yes, 1994
We consider integral equations on the half-line of the form and the finite section approximation to x obtained by replacing the infinite limit of integration by the finite limit β.
Chandler-Wilde, SN
core  

Home - About - Disclaimer - Privacy