Results 81 to 90 of about 7,062,891 (319)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Logarithmic singularity subtraction for matrix‐friendly layered medium Green's functions

open access: yesElectronics Letters
A subtraction procedure is proposed to evaluate the logarithmic singularity for matrix‐friendly layered medium Green's functions. In this subtraction procedure, an integral of the Bessel function combined with the exponential function and power function,
Shuo Wang
doaj   +1 more source

Localized boundary-domain integral equation formulation for mixed type problems [PDF]

open access: yes, 2010
Copyright @ 2010 Walter de Gruyter GmbHSome modified direct localized boundary-domain integral equations (LBDIEs) systems associated with the mixed boundary value problem (BVP) for a scalar “Laplace” PDE with variable coefficient are formulated and ...
Mikhailov, SE   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Numerical Solution of Weakly Singular Ito-Volterra Integral Equations via Operational Matrix Method based on Euler Polynomials

open access: yesپژوهش‌های ریاضی, 2018
Introduction Many problems which appear in different sciences such as physics, engineering, biology, applied mathematics and different branches can be modeled by using deterministic integral equations.
Farshid Mirzaee, Nasrin Samadyar;
doaj  

Solutions of singular integral equations

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1982
Qualitative behavior of solutions of possibly singluar integral equations is studied. It includes properties such as positivity, boundedness and monotonicity of the solutions of the infinite interval.
Rina Ling
doaj   +1 more source

A class of Runge–Kutta methods for nonlinear Volterra integral equations of the second kind with singular kernels

open access: yesAdvances in Difference Equations, 2018
This paper aims to obtain an approximate solution for fractional order Riccati differential equations (FRDEs). FRDEs are equivalent to nonlinear Volterra integral equations of the second kind.
Bijan Hasani Lichae   +2 more
doaj   +1 more source

On the approximation of linear integral equations

open access: yes, 1976
Integral equations form an important subject with applied mathematics due to their occurence in a variety of models of physical problems. The intent of this thesis is to present in a simple and concise manner the theory of integral equations in the ...
Ali, Agha I.
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy