Results 81 to 90 of about 7,062,891 (319)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Logarithmic singularity subtraction for matrix‐friendly layered medium Green's functions
A subtraction procedure is proposed to evaluate the logarithmic singularity for matrix‐friendly layered medium Green's functions. In this subtraction procedure, an integral of the Bessel function combined with the exponential function and power function,
Shuo Wang
doaj +1 more source
Localized boundary-domain integral equation formulation for mixed type problems [PDF]
Copyright @ 2010 Walter de Gruyter GmbHSome modified direct localized boundary-domain integral equations (LBDIEs) systems associated with the mixed boundary value problem (BVP) for a scalar “Laplace” PDE with variable coefficient are formulated and ...
Mikhailov, SE +5 more
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Introduction Many problems which appear in different sciences such as physics, engineering, biology, applied mathematics and different branches can be modeled by using deterministic integral equations.
Farshid Mirzaee, Nasrin Samadyar;
doaj
Solutions of singular integral equations
Qualitative behavior of solutions of possibly singluar integral equations is studied. It includes properties such as positivity, boundedness and monotonicity of the solutions of the infinite interval.
Rina Ling
doaj +1 more source
This paper aims to obtain an approximate solution for fractional order Riccati differential equations (FRDEs). FRDEs are equivalent to nonlinear Volterra integral equations of the second kind.
Bijan Hasani Lichae +2 more
doaj +1 more source
On the approximation of linear integral equations
Integral equations form an important subject with applied mathematics due to their occurence in a variety of models of physical problems. The intent of this thesis is to present in a simple and concise manner the theory of integral equations in the ...
Ali, Agha I.
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

