Results 71 to 80 of about 7,062,891 (319)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Differential-integral Euler–Lagrange equations [PDF]
Iranian Journal of Numerical Analysis and OptimizationWe study the calculus of variations problem in the presence of a system of differential-integral (D-I) equations. In order to identify the necessary optimality conditions for this problem, we derive the so-called D-I Euler–Lagrange equations.
Mohammedd Shehata
doaj +1 more source
The effect of near-zone preconditioning on electromagnetic integral equations of first and second kind [PDF]
Advances in Radio Science, 2013 The linear equation systems which arise from the discretization of surface integral equations are conveniently solved with iterative methods because of the possibility to employ fast integral methods like the Multilevel Fast Multipole Method.
O. Wiedenmann, T. F. Eibert
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Hypersingular Integral Equations Encountered in Problems of Mechanics
MathematicsIn the paper, for hypersingular integral equations with new kernels, a solution is constructed using an approach based on Chebyshev orthogonal polynomials and the principle of contraction mappings.
Suren M. Mkhitaryan +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Integral equations for the wave function of particle systems
Semiconductor Physics, Quantum Electronics & Optoelectronics, 2019 Constructions of integral equations to the wave function of particle systems in bound state have been proposed in this work. We obtain the kernel of the Fredholm type integral equation for an odd number of particles in explicit form. Besides, an integral
K.V. Avdonin
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