Results 161 to 170 of about 108,806 (312)

Solving linear Fredholm-Stieltjes integral equations of the second kind by using the generalized Simpson’s rule

MANAS: Journal of Engineering, 2016
In this paper, the generalized Simpson's rule (GSR) is applied to solve linear Fredholm-Stieltjes integral equations of the second kind (LFSIESK). A numerical example is presented to illustrate the method by using Maple.
A. Asanov, S. Yanık
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Singular perturbations of integral equations with degenerate kernels [PDF]

, 1996
Singularly perturbed Fredholm equations of the second kind are investigated. The kernels are allowed to have a jump discontinuity which vanishes at a point along the diagonal.
Shubin, Carol Ann
core   +1 more source

On Laplace's Integral Equations [PDF]

Transactions of the American Mathematical Society, 1926
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Rational Interpolation and Approximate Solution of Integral Equations [PDF]

, 2012
In the space of continuous periodic functions, we construct interpolation rational operators, use them to obtain quadrature formulas with positive coefficients which are exact on rational trigonometric functions of order 2n, and suggest an algorithm for ...
Русак, Валентин Николаевич, Гриб, Николай Васильевич   +1 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Analysis of boundary-domain Integral equations based on a new parametrix for the mixed diffusion BVP with variable coefficient in an interior Lipschitz domain [PDF]

, 2018
A mixed boundary value problem for the partial differential equation of difusion in an inhomogeneous medium in a Lipschitz domain is reduced to a system of direct segregated parametrix-based Boundary-Domain Integral Equations (BDIEs). We use a parametrix
Mikhailov, SE, Portillo, C
core  

Field-only surface integral equations: scattering from a dielectric body. [PDF]

J Opt Soc Am A Opt Image Sci Vis, 2020
Sun Q, Klaseboer E, Yuffa AJ, Chan DYC.
europepmc   +1 more source