Results 151 to 160 of about 108,806 (312)
Journal of Integral Equations and Applications, 2004 The author discusses the adsorption integral equation which describes the relationship between the measured adsorption isotherm and the unknown energy distribution function. Firstly he reduces the equation to the Langmuir integral equation, then shows that under rather general assumption the equation can be solved in an analytical form.
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Integral zeroes of Krawtchouk polynomials [PDF]
, 2012 This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.Krawtchouk polynomials appear in many various areas of mathematics starting from discrete mathematics (e.g., in coding theory), association schemes, and in ...
Alenezi, Ahmad M
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
On the Theory of an Integral Equation
Advances in Applied Mathematics, 1994 The main object of the study in the paper is the following integral equation (1) \(x(t) = f(t) - \mu \int^ \infty_ 0 K(\tau) \text{sign} [x(t - \tau)] d \tau\). Here it is assumed that \(\mu \geq 0\), \(f\) is a continuous function having only isolated zeros \(t_ k\) such that \(f'(t_ k) \neq 0\) for \(k=1,2, \dots\). Moreover, the kernel function \(K\)
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Numerical Solution of Locally Loaded Volterra Integral Equations
ComputationLoaded Volterra integral equations represent a novel class of integral equations that have attracted considerable attention in recent years due to their numerous applications in various fields of science and engineering.
Vladislav Byankin +3 more
doaj +1 more source
Integral equations and product integrals [PDF]
Pacific Journal of Mathematics, 1966 openaire +2 more sources
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Solution of a singular integral equation by a split-interval method [PDF]
, 2007 The article is available at http://www.math.ualberta.ca/ijnam/Volume-4-2007/No-1-07/2007-01-05.pdf. This article is not available through the Chester Digital RepositoryThis article discusses a new numerical method for the solution of a singular integral ...
Ford, Neville J. +3 more
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