Results 141 to 150 of about 108,480 (312)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The numerical solution of a Fredholm integral equations of the second kind by the weighted optimal quadrature formula

Results in Applied Mathematics
This work considers the optimal quadrature formula in a Hilbert space for the numerical approximation of the integral equations. It discusses the sequence of solving integral equations with quadrature formulas.
Abdullo Hayotov, Samandar Babaev
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Adsorption Integral Equation

Journal of Integral Equations and Applications, 2004
The author discusses the adsorption integral equation which describes the relationship between the measured adsorption isotherm and the unknown energy distribution function. Firstly he reduces the equation to the Langmuir integral equation, then shows that under rather general assumption the equation can be solved in an analytical form.
openaire   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Mesh-based numerical implementation of the localized boundary-domain integral equation method to a variable-coefficient Neumann problem

, 2005
An implementation of the localized boundary-domain integral-equation (LBDIE) method for the numerical solution of the Neumann boundary-value problem for a second-order linear elliptic PDE with variable coefficient is discussed.
Mikhailov, SE, Nakhova, IS
core  

Integral zeroes of Krawtchouk polynomials [PDF]

, 2012
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.Krawtchouk polynomials appear in many various areas of mathematics starting from discrete mathematics (e.g., in coding theory), association schemes, and in ...
Alenezi, Ahmad M
core  

Positive solutions of Volterra integral equations using integral inequalities

Journal of Inequalities and Applications, 2002
The existence of positive solutions of certain special cases of the possibly singular Volterra integral equation is discussed, using Krasnoselskii's fixed point theorem.
O'regan Donal, Meehan Maria
doaj  

Integrability and Einstein׳s Equations

Integrable structures arise in general relativity when the spacetime possesses a pair of commuting Killing vectors admitting 2-spaces orthogonal to the group orbits. The physical interpretation of such spacetimes depends on the norm of the Killing vectors.
Korotkin, Dmitry, Samtleben, Henning
openaire   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source