Results 111 to 120 of about 286,104 (297)
University Outdoor Activities: an integral approach in the professional formation
Podium, 2012 The work is lead to establish the theoretical foundations of the university outdoor labour from the organizational forms of the teaching process that favour the knowledge acquisition and the development of necessary skills in the students to promote ...
María Ofelia Armas-Álvarez
doaj
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Integral human formation of EPTNM students: teaching proposal by the ABP
, 2022 This educational product is a teaching proposal developed from the research conducted in the Professional Master’s Degree in Professional and Technological Education – PROFEPT, resulting from the dissertation entitled “Project-Based Learning (PBL) in the
Melo, Joice de Lima +1 more
core
Prerequisites for the formation of Neostructuralism as an integral linguistic paradigm
Слово.ру: балтийский акцентThis work is the result of methodological reflection related to the comprehension of more than two hundred years of experience accumulated since the secularization of linguistics, and the formation of a reasonable forecast regarding the near and medium ...
Kravchenko M.A.
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
A space to promote culture, identity and patrimony at the Faculty of Physical Culture
Cultura Física y Deportes de Guantánamo, 2015 This investigation introduces a study about the relationship culture- identity- cultural patrimony in Guantánamo, needed for the formation of an adequate General and Integral Culture at the Faculty of Physical Culture in the students.
Eyler Guerra-Pérez +1 more
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source