Results 241 to 250 of about 483,479 (332)

Global Maxwell Tomography Using the Volume-Surface Integral Equation for Improved Estimation of Electrical Properties. [PDF]

IEEE Trans Biomed Eng
Giannakopoulos II, Serralles JEC, Paska J, Cloos MA, Brown R, Lattanzi R.   +5 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Functional equation modeling of adaptive operant-control systems via Matkowski fixed point theory. [PDF]

PLoS One
Monica S, Ramesh Kumar D.
europepmc   +1 more source

2D/3D mixed frontal projection system based on integral imaging

, 2020
Huan Deng, Qiang Li, Wei He, Xiaowei Li, Hui Ren, Cong Chen   +5 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Multiparametric Breast MRI for the Differentiation of Atypical Ductal Hyperplasia and Ductal Carcinoma In Situ in Postmenopausal Women. [PDF]

Cureus
Mihajlovic MN, Raspopovic LJ, Dimitrijevic D, Krusac IB, Djajic A, Nadrljanski MM.   +5 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Multi-modal AI in precision medicine: integrating genomics, imaging, and EHR data for clinical insights. [PDF]

Front Artif Intell
Khan SN, Danishuddin, Khan MWA, Guarnera L, Akhtar SMF.   +4 more
europepmc   +1 more source

Three-dimensional integral imaging in photon-starved environments with high-sensitivity image sensors

, 2019
Adam Markman, Timothy O’Connor, Hisaya Hotaka, Shinji Ohsuka, Bahram Javidi   +4 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source