Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Comparative Assessment of Graglia-Wilton-Peterson and Rao-Wilton-Glisson Basis Functions for Radiofrequency Coil Modeling in Magnetic Resonance Imaging. [PDF]
Franzò D +4 more
europepmc +1 more source
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Direct experimental test of Feynman's path integral postulates with single photons. [PDF]
Wen YL +8 more
europepmc +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Valgus bracing can relocate cartilage contact pressure away from bone marrow lesions and full-thickness cartilage defects in varus-malaligned medial knee osteoarthritis. [PDF]
Starkey SC +7 more
europepmc +1 more source
Revealing Hidden Dynamics of Hydrogel-Based Desalination with <sup>23</sup>Na Nuclear Magnetic Resonance. [PDF]
Zou H +5 more
europepmc +1 more source
Amyloid-related imaging abnormalities after immunotherapy: How might brain microvascular basement membrane components be involved? [PDF]
Vinters HV, Magaki S.
europepmc +1 more source
Arrhythmogenic Mitral Valve Prolapse: Looking Beyond Mitral Regurgitation. [PDF]
Ribeyrolles S +8 more
europepmc +1 more source
Fix or freeze? Spectral differences arising from tissue preparation in chemical imaging.
Zheng T +3 more
europepmc +1 more source

