Results 251 to 260 of about 483,479 (332)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Breast MRI in the Assessment of Internal Thoracic Lymph Nodes: Morphodynamic and Functional Criteria for Detection of Metastatic Lymph Nodes. [PDF]

Cureus
Nadrljanski MM, Raspopovic LJ, Dimitrijevic D, Krusac IB, Mihajlovic MN, Djajic A.   +5 more
europepmc   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Biologically Guided Gamma Knife Dose Painting for Recurrent High-Grade Gliomas: A Retrospective Study Using Functional MRI Techniques. [PDF]

Med Sci Monit
Seyithanoğlu MH, Yurtsever İ, Gundag Papaker M, Mutluer AS, Dundar TT, Kitis S, Akdur K, Mayadağlı A.   +7 more
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

The nature of HHL 73 from optical imaging and Integral Field Spectroscopy

, 2007
R. J. Garcı́a López, S. F. Sánchez, B. García‐Lorenzo, R. Estalella, A. Riera, G. Busquet   +5 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Adaptation of a small animal radiation research platform for pre-clinical microbeam irradiations. [PDF]

Med Phys
Yeomans L, Gharehkhani K, Cummings C, Wilk J, Box C, Nill S, Oelfke U.   +6 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Assessment of the Optimal Distal End Length of Echogenic Perineural Catheters to Facilitate Successful Coiling: A Regional Anesthesia Simulator-Based Technical Study. [PDF]

Cureus
Riga M, Poulogiannopoulou E, Panagouli K, Zeneli E, Papadimos T, Saranteas T.   +5 more
europepmc   +1 more source