Results 31 to 40 of about 4,454 (298)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Homology Groups in Warped Product Submanifolds in Hyperbolic Spaces

open access: yesJournal of Mathematics, 2021
In this paper, we show that if the Laplacian and gradient of the warping function of a compact warped product submanifold Ωp+q in the hyperbolic space ℍm−1 satisfy various extrinsic restrictions, then Ωp+q has no stable integral currents, and its ...
Yanlin Li   +3 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

The two-sphere partition function from timelike Liouville theory at three-loop order

open access: yesJournal of High Energy Physics, 2022
While the Euclidean two-dimensional gravitational path integral is in general highly fluctuating, it admits a semiclassical two-sphere saddle if coupled to a matter CFT with large and positive central charge. In Weyl gauge this gravity theory is known as
Beatrix Mühlmann
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Fourier integrals and a new representation of Maslov's canonical operator near caustics [PDF]

open access: yes, 2013
We suggest a new representation of Maslov's canonical operator in a neighborhood of the caustics using a special class of coordinate systems (\eikonal coordinates") on Lagrangian ...
Dobrokhotov, Sergey   +2 more
core  

On Integral Manifolds for Leibniz Algebras [PDF]

open access: yesAlgebra, 2014
We discuss several partial solutions to the so-called “coquecigrue problem” of Loday; these solutions parallel, but also generalize in several directions, the classical Lie group-Lie algebra correspondence. Our study highlights some clear similarities between the split and nonsplit cases and leads us to a general unifying scheme that provides an answer
Juan Monterde, Fausto Ongay
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

On symplectic 4-manifolds and contact 5-manifolds [PDF]

open access: yes, 2008
In dieser Arbeit werden einige Aussagen über symplektische Strukturen auf 4-dimensionalen Mannigfaltigkeiten und Kontaktstrukturen auf 5-dimensionalen Mannigfaltigkeiten bewiesen.
Hamilton, Mark
core  

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