Results 41 to 50 of about 4,454 (298)

Superpotentials of D-branes in Calabi-Yau manifolds with several moduli by mirror symmetry and blown-up

open access: yesJournal of High Energy Physics, 2022
We study B-brane superpotentials depending on several closed- and open-moduli on Calabi-Yau hypersurfaces and complete intersections. By blowing up the ambient space along a curve wrapped by B-branes in a Calabi-Yau manifold, we obtain a blow-up new ...
Xuan Li, Yuan-Chun Jing, Fu-Zhong Yang
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Integral Manifolds of the Charged Three-Body Problem [PDF]

open access: yes, 2017
This thesis is dedicated to the study of the In- tegral Manifolds of the Charged Three-Body Problem. My aim is to give a mathematical analysis of the physical mechanical system that consists of three charged particles moving in space and interacting via ...
Zaman, Mohammad
core   +3 more sources

Hyperbolic Volumes of Two Bridge Cone-Manifolds

open access: yesИзвестия Иркутского государственного университета: Серия "Математика"
In this paper we investigate the existence of hyperbolic, Euclidean and spherical structures on cone-manifolds with underlying space 3-sphere and with singular set a given two-bridge knot.
A. D. Mednykh, A. B. Qutbaev
doaj   +1 more source

Chern classes of integral submanifolds of some contact manifolds

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
A complex subbundle of the normal bundle to an integral submanifold of the contact distribution in a Sasakian manifold is given. The geometry of this bundle is investigated and some results concerning its Chern classes are obtained.
Gheorghe Pitiş
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

NONCLASSICAL SPECTRAL ASYMPTOTICS AND DIXMIER TRACES: FROM CIRCLES TO CONTACT MANIFOLDS

open access: yesForum of Mathematics, Sigma, 2017
We consider the spectral behavior and noncommutative geometry of commutators $[P,f]$ , where ...
HEIKO GIMPERLEIN, MAGNUS GOFFENG
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Rigidity Phenomena of Group Actions on a Class of Nilmanifolds and Anosov R^n Actions [PDF]

open access: yes, 1992
An action of a group Г on a manifold M is a homomorphism ρ from Г to Diff(M). ρo is locally rigid if the nearby homomorphism ρ, ρ(γ) = h o ρ0, (γ) 0h^(-1) for some h Є Diff(M) and for all, γ Є Г.
Qian, Nantian
core   +1 more source

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