Results 91 to 100 of about 33,262 (259)

On the Convergence of the Approximate Solution to the Optimization Problem for Oscillatory Processes

Қарағанды университетінің хабаршысы. Математика сериясы
This article addresses the non-linear optimization problem of oscillatory processes governed by partial integro-differential equations involving a Fredholm integral operator. A distinctive feature of the problem is that both the objective functional and
E.F. Abdyldaeva, A. Kerimbekov, T.K. Yuldashev, M. Kamali   +3 more
doaj   +1 more source

Starlikeness Properties of a New Integral Operator for Meromorphic Functions

Journal of Applied Mathematics, 2011
We define here an integral operator ℋ𝛾1,…,𝛾𝑛 for meromorphic functions in the punctured open unit disk. Several starlikeness conditions for the integral operator ℋ𝛾1,…,𝛾𝑛 are derived.
Aabed Mohammed, Maslina Darus
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

New Integral Operator for Analytic Functions

Journal of Function Spaces
Let Apn be the class of functions fz given by fz=zp+ap+nzp+n+ap+n+1zp+n+1+⋯ which are analytic in the open unit disk U. For fz∈Apn, new integral operators O−jfz and Ojfzj=0,1,2,⋯. are considered.
H. Özlem Güney, Shigeyoshi Owa, Adel A. Attiya   +2 more
doaj   +1 more source

A Random Riemann–Liouville Integral Operator

Mathematics
In this work, we propose a definition of the random fractional Riemann–Liouville integral operator, where the order of integration is given by a random variable.
Jorge Sanchez-Ortiz, Omar U. Lopez-Cresencio, Martin P. Arciga-Alejandre, Francisco J. Ariza-Hernandez   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Starlike integral operators [PDF]

Pacific Journal of Mathematics, 1978
Miller, Sanford S., Mocanu, Petru T., Reade, Maxwell O.   +2 more
openaire   +2 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source