Results 71 to 80 of about 659,470 (267)

A fixed-point type result for some non-differentiable Fredholm integral equations

open access: yesMathematical Modelling and Analysis
In this paper, we present a new fixed-point result to draw conclusions about the existence and uniqueness of the solution for a nonlinear Fredholm integral equation of the second kind with non-differentiable Nemytskii operator.
Miguel A. Hernández-Verón   +3 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Real and Complex Techniques in Harmonic Analysis from the Point of View of Covariant Transform

open access: yes, 2014
This note reviews complex and real techniques in harmonic analysis. We describe a common source of both approaches rooted in the covariant transform generated by the affine group.
Kisil, Vladimir V.
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Convolution Integral Operators

open access: yesSiberian Mathematical Journal, 2018
The author considers the space $L_2:=L_2(\mathbb{R}^N)$ consisting of the measurable and square-integrable functions on $\mathbb{R}^{N}$. As in the work by \textit{L. Hörmander} [Acta Math. 104, 93--140 (1960; Zbl 0093.11402)], the author considers the space $L_2^2$ being the set of all continuous linear operators in $L_2$ which commute with shifts ...
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Ozaki's conditions for general integral operator [PDF]

open access: yesSahand Communications in Mathematical Analysis, 2017
Assume that $mathbb{D}$ is the open unit disk. Applying Ozaki's conditions, we consider two classes of locally univalent, which denote by $mathcal{G}(alpha)$ and $mathcal{F}(mu)$ as follows begin{equation*}  mathcal{G}(alpha):=left{fin mathcal{A ...
Rahim Kargar, Ali Ebadian
doaj  

Properties of a new integral operator

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2016
In this paper, we derive sufficient conditions for the univalence, star- likeness, convexity and some other properties in the class N (ρ) ; for a new integral operator defined on the space of normalized analytic functions in the open unit disk.
Bucur Roberta   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy