Results 101 to 110 of about 656,740 (269)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

On the Convergence of the Approximate Solution to the Optimization Problem for Oscillatory Processes

Қарағанды университетінің хабаршысы. Математика сериясы
This article addresses the non-linear optimization problem of oscillatory processes governed by partial integro-differential equations involving a Fredholm integral operator. A distinctive feature of the problem is that both the objective functional and
E.F. Abdyldaeva, A. Kerimbekov, T.K. Yuldashev, M. Kamali   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Unbounded Integral Hankel Operators

Functional Analysis and Its Applications
For a wide class of unbounded integral Hankel operators on the positive half-line, we prove essential self-adjointness on the set of smooth compactly supported functions.
Pushnitski, Alexander, Treil, Sergei
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Sufficient Conditions for Univalence of an Integral Operator

Journal of Inequalities and Applications, 2008
In this paper we have introduced an integral general operator. For this general operator which is a generalization of more known integral operators we have demonstrated some univalence properties.
Daniel Breaz, Gheorghe Oros, Georgia Irina Oros   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

New Integral Operator for Analytic Functions

Journal of Function Spaces
Let Apn be the class of functions fz given by fz=zp+ap+nzp+n+ap+n+1zp+n+1+⋯ which are analytic in the open unit disk U. For fz∈Apn, new integral operators O−jfz and Ojfzj=0,1,2,⋯. are considered.
H. Özlem Güney, Shigeyoshi Owa, Adel A. Attiya   +2 more
doaj   +1 more source

A Random Riemann–Liouville Integral Operator

Mathematics
In this work, we propose a definition of the random fractional Riemann–Liouville integral operator, where the order of integration is given by a random variable.
Jorge Sanchez-Ortiz, Omar U. Lopez-Cresencio, Martin P. Arciga-Alejandre, Francisco J. Ariza-Hernandez   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source