Results 101 to 110 of about 527,109 (283)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Integral representations for Padé-type operators
Journal of Applied Mathematics, 2002 The main purpose of this paper is to consider an explicit form of the Padé-type operators. To do so, we consider the representation of Padé-type approximants to the Fourier series of the harmonic functions in the open disk and of the L p-functions on the
Nicholas J. Daras
doaj +1 more source
Starlike integral operators [PDF]
Pacific Journal of Mathematics, 1978 Miller, Sanford S. +2 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Boundedness for a Class of Singular Integral Operators on Both Classical and Product Hardy Spaces
Abstract and Applied Analysis, 2014 We found that the classical Calderón-Zygmund singular integral operators are bounded on both the classical Hardy spaces and the product Hardy spaces. The purpose of this paper is to extend this result to a more general class. More precisely, we introduce
Chaoqiang Tan
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On Positive Definite Kernels of Integral Operators Corresponding to the Boundary Value Problems for Fractional Differential Equations. [PDF]
Entropy (Basel), 2022 Aleroev M, Aleroev T.
europepmc +1 more source
Analytic Singular Integral Operators [PDF]
American Journal of Mathematics, 1967 The following paper extends to real analytic manifolds the general theory of singular integral operators as described in [lO] and [13]. The definition of an analytic singular integral operator is made in terms of the kernel of the operator. The symbol of the operator is discussed and in the case of an elliptic operator, a regularity theorem is proved ...
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source