Results 71 to 80 of about 1,114,507 (286)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structure and Process: Integral Philosophy and the Triple Transformation [PDF]

open access: yesIntegral Review, 2012
This paper looks at the ongoing debate between perennialism and pluralism in religious studies and considers the category of the integral, as described by Sri Aurobindo (1872-1950) in the context of this debate.
Debashish Banerji
doaj  

Segni dei tempi, sinodalità, "gender" [PDF]

open access: yes, 2019
My analysis on the category of signs of times (SoT) shows how it can help to explain a few aspects of synodality. I will explain how synodality and SoT support each other and why Synods should teach a correct judgment of SoT. It is a way to educate God's
Migliorini, Damiano
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Estado Forte em combate ao Liberalismo: o projeto antissemita integralista de Gustavo Barroso para o Brasil dos anos 1930; Estado fuerte en combate al liberalismo: el proyecto antisemita integralista de Gustavo Barroso para el Brasil de los años 1930; Strong State in the fight against Liberalism: the integralist anti-Semitic project of Gustavo Barroso for Brazil in the 1930s

open access: yesRevista nuestrAmérica, 2019
Resumo: O projeto integralista almejado por Gustavo Barroso baseava-se no modelo de Estado forte. Diferente da postura de Plínio Salgado e Miguel Reale, que não carregavam o racismo contra a figura do judeu, Barroso pensa a formação do novo Brasil com a ...
Cicero João da Costa Filho
doaj  

Review of Thomas Crean and Alan Fimister, Integralism: A Manual of Political Philosophy

open access: yesJournal of Moral Theology, 2021
Review of Thomas Crean and Alan Fimister, _Integralism: A Manual of Political ...
Kent Lasnoski
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Reality of the Refugee Crisis in Italy: A Look into the Lives of Illegitimate Refugees and the Unofficial Organizations That Support Them [PDF]

open access: yes, 2018
The words written on the United States of America’s famous Statue of Liberty, written by poet Emma Lazarus over a century ago: Give me your tired, your poor, your huddled masses yearning to breathe free The wretched refuse of your teeming shore ...
McQuirk, Cole
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

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