Results 221 to 230 of about 31,378 (281)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Neonatal pain in a broader perspective: an analysis through systems thinking. [PDF]

open access: yesRev Esc Enferm USP
Naujorks S   +4 more
europepmc   +1 more source

Patient satisfaction and digital health in primary health care: a scoping review protocol. [PDF]

open access: yesFront Public Health
Xavier PB   +6 more
europepmc   +1 more source

Integrating Genomes

Science, 2012
As genomic sequencing projects attempt ever more ambitious integration of genetic, molecular, and phenotypic information, a specialization of genomics has emerged, embodied in the subdiscipline of computational genomics. Models inherited from population genetics, phylogenetics, and human disease genetics merge with those from graph theory,
Zerbino, D. R., Paten, B., Haussler, D.
openaire   +2 more sources

Integration Workbench: Integrating Schema Integration Tools

22nd International Conference on Data Engineering Workshops (ICDEW'06), 2006
A key aspect of any data integration endeavor is establishing a transformation that translates instances of one or more source schemata into instances of a target schema. This schema integration task must be tackled regardless of the integration architecture or mapping formalism. In this paper we provide a task model for schema integration. We use this
P. Mork   +3 more
openaire   +1 more source

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