Results 241 to 250 of about 8,166 (301)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Recoverable robust single machine scheduling with polyhedral uncertainty. [PDF]

J Sched
Bold M, Goerigk M.
europepmc   +1 more source

Suicide prevention starts before the crisis: intervention guidelines for university students. [PDF]

Psicol Reflex Crit
Cecchin HFG, Murta SG.
europepmc   +1 more source

Patient satisfaction and digital health in primary health care: a scoping review protocol. [PDF]

Front Public Health
Xavier PB, Silva ÍS, Dantas THM, Lopes RH, de Araújo AJ, de Figueirêdo RC, Uchôa SADC.   +6 more
europepmc   +1 more source

Integrality gaps for colorful matchings [PDF]

Discrete Optimization, 2019
We study the integrality gap of the natural linear programming relaxation for the Bounded Color Matching (BCM) problem. We provide several families of instances and establish lower bounds on their integrality gaps and we study how the Sherali-Adams "lift-
Steven Kelk, Georgios Stamoulis
exaly   +2 more sources

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‘Integronsters’, integral and integrated modeling

Environmental Modelling & Software, 2013
In many cases model integration treats models as software components only, ignoring the fluid relationship between models and reality, the evolving nature of models and their constant modification and recalibration. As a result, with integrated models we find increased complexity, where changes that used to impact only relatively contained models of ...
Alexey A. Voinov, Herman H. Shugart
openaire   +1 more source

Integration Workbench: Integrating Schema Integration Tools

22nd International Conference on Data Engineering Workshops (ICDEW'06), 2006
A key aspect of any data integration endeavor is establishing a transformation that translates instances of one or more source schemata into instances of a target schema. This schema integration task must be tackled regardless of the integration architecture or mapping formalism. In this paper we provide a task model for schema integration. We use this
Peter Mork, Arnon Rosenthal, Leonard J. Seligman, Joel Korb, Ken Samuel   +4 more
openaire   +1 more source