Results 41 to 50 of about 31,378 (281)

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Discreteness and integrality in Conformal Field Theory

open access: yesJournal of High Energy Physics, 2021
Various observables in compact CFTs are required to obey positivity, discreteness, and integrality. Positivity forms the crux of the conformal bootstrap, but understanding of the abstract implications of discreteness and integrality for the space of CFTs
Justin Kaidi, Eric Perlmutter
doaj   +1 more source

Rounding Algorithms for a Geometric Embedding of Minimum Multiway Cut

open access: yes, 2003
The multiway-cut problem is, given a weighted graph and k >= 2 terminal nodes, to find a minimum-weight set of edges whose removal separates all the terminals.
Karger, David   +4 more
core   +3 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Study of Mobile Internet Security Risk and End-to-End Service Security Evaluation

open access: yesDianxin kexue, 2013
The mobile internet architecture and its security risks were introduced.Then the index system of evaluation was discussed,which mainly included confidentiality,integrity,availability,reliability,safety and performability.In the end,a method was proposed ...
Rong Yue, Hong Li
doaj  

Integrality of the human being and the care in the health-disease process

open access: yesCultura de los Cuidados, 2019
Introduction: Integrality is associated with the various dimensions of life, considering the tangible and subjective aspects related to the complex unity of the human being.
Iara Micheline Pereira Correa   +3 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Integrality gaps of semidefinite programs for Vertex Cover and relations to $\ell_1$ embeddability of Negative Type metrics [PDF]

open access: yes, 2006
We study various SDP formulations for {\sc Vertex Cover} by adding different constraints to the standard formulation. We show that {\sc Vertex Cover} cannot be approximated better than $2-o(1)$ even when we add the so called pentagonal inequality ...
Hatami, Hamed   +2 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

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