Results 61 to 70 of about 8,166 (301)

Forming the integrality in health concept based on the historical-cultural approach

open access: yesRevista Eletrônica de Enfermagem, 2015
This study analyzed the formation of the concept integrality in health by undergraduate students of the nursing bachelor and licensure course in a historical-cultural approach.
Rosangela Andrade Aukar de Camargo   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A new method for evaluating the rock mass damage index based on the field point load strength [PDF]

open access: yesRoyal Society Open Science, 2019
The damage index is a crucial controlling parameter for rock mass strength and deformation in civil, geological and mining engineering projects. In this study, a new method was proposed for computing the damage index of a rock mass based on the field ...
Lei Wen   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Integrality of instanton numbers and p-adic B-model

open access: yes, 2006
We study integrality of instanton numbers (genus zero Gopakumar–Vafa invariants) for quintic and other Calabi–Yau manifolds. We start with the analysis of the case when the moduli space of complex structures is one-dimensional; later we show that our ...
Vologodsky, Vadim   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Testing additive integrality gaps [PDF]

open access: yes, 2013
We consider the problem of testing whether the maximum additive integrality gap of a family of integer programs in standard form is bounded by a given constant.
Gennady Shmonin   +7 more
core   +3 more sources

On explicit formulae of LMOV invariants

open access: yesJournal of High Energy Physics, 2019
We started a program to study the open string integrality invariants (LMOV invariants) for toric Calabi-Yau 3-folds with Aganagic-Vafa brane (AV-brane) several years ago. This paper is devoted to the case of resolved conifold with one out AV-brane in any
Shengmao Zhu
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Hyperelliptic Integrals to Elliptic Integrals

open access: yesProceedings of the 2023 International Symposium on Symbolic and Algebraic Computation, 2023
Consider a hyperelliptic integral $I=\int P/(Q\sqrt{S}) dx$, $P,Q,S\in\mathbb{K}[x]$, with $[\mathbb{K}:\mathbb{Q}]<\infty$. When $S$ is of degree $\leq 4$, such integral can be calculated in terms of elementary functions and elliptic integrals of three kinds $\mathcal{F},\mathcal{E},Π$.
openaire   +3 more sources

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