Results 91 to 100 of about 19,019 (189)

Discovery and Preclinical Profiling of GSK3839919, a Potent HIV-1 Allosteric Integrase Inhibitor. [PDF]

ACS Med Chem Lett, 2022
Parcella K, Parcella K, Wang T, Eastman K, Zhang Z, Yin Z, Patel M, Tu Y, Zheng BZ, Walker MA, Saulnier MG, Frennesson D, Bowsher M, Gillis E, Peese K, Belema M, Cianci C, Dicker IB, McAuliffe B, Ding B, Falk P, Simmermacher J, Parker DD, Sivaprakasam P, Kish K, Lewis H, Hanumegowda U, Jenkins S, Kadow JF, Krystal M, Meanwell NA, Naidu BN.   +31 more
europepmc   +1 more source

Madurahydroxylactone Derivatives as Dual Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and RNase H [PDF]

, 2007
Christophe Marchand, John A. Beutler, Antony Wamiru, Scott R. Budihas, Ute Möllmann, Lothar Heinisch, John W. Mellors, S F Le Grice, Yves Pommier   +8 more
openalex   +1 more source

Changes in Body Mass Index with Longer-term Integrase Inhibitor Use: A Longitudinal Analysis of Data from the Randomized Trial to Prevent Vascular Events in Human Immunodeficiency Virus (REPRIEVE). [PDF]

Clin Infect Dis, 2023
Kileel EM, Malvestutto CD, Lo J, Fitch KV, Fichtenbaum CJ, Aberg JA, Zanni MV, Martinez E, Okeke NL, Kumar P, Joao E, Bares SH, Berrner D, Smieja M, Roa JC, McCallum S, Douglas PS, Ribaudo HJ, Grinspoon SK.   +18 more
europepmc   +1 more source

Microarray Compound Screening (μARCS) to Identify Inhibitors of HIV Integrase

, 2002
Caroline A. David, Tim Middleton, Debra Montgomery, Hock Ben Lim, Warren M. Kati, Akhter Molla, Xiaoling Xuei, Usha Warrior, James L. Kofron, David J. Burns   +9 more
openalex   +1 more source

Synthesis and anti-HIV evaluation of hybrid-type prodrugs conjugating HIV integrase inhibitors with d4t by self-cleavable spacers containing an amino acid residue [PDF]

, 2007
Christine Fossey, Ngoc Trinh Huynh, Anh-Hoang Vu, Anamaria Vidu, Irina Zarafu, D. LADUREE, Sylvie Schmidt, Géraldine Laumond, Anné-Marie Aubertin   +8 more
openalex   +1 more source

Integrase Inhibitor Use Associated with Weight Gain in Women and Incident Diabetes Mellitus. [PDF]

AIDS Res Hum Retroviruses, 2022
Asundi A, Olson A, Jiang W, Varshney SP, White LF, Sagar M, Lin NH.   +6 more
europepmc   +1 more source

Styrylquinolines, Integrase Inhibitors Acting Prior to Integration: a New Mechanism of Action for Anti-Integrase Agents

, 2004
Sabine Bonnenfant, Claire M. Thomas, Claudio Vita, Frédéric Subra, Eric Deprez, Fatima Zouhiri, Didier Desmaële, Jean d’Angelo, Jean François Mouscadet, Hervé Leh   +9 more
openalex   +1 more source

Mutations Associated with Failure of Raltegravir Treatment Affect Integrase Sensitivity to the Inhibitor In Vitro [PDF]

, 2008
Isabelle Malet, Olivier Delelis, Marc‐Antoine Valantin, Brigitte Montès, Cathia Soulié, Marc Wirden, Luba Tchertanov, Gilles Peytavin, Jacques Reynes, Jean‐François Mouscadet, Christine Katlama, Vincent Cálvez, Anne‐Geneviève Marcelin   +12 more
openalex   +1 more source

Raltegravir: a potent and safe integrase inhibitor with a favourable impact on cardiovascular and liver profile [PDF]

, 2008
Francisco J. Blanco, Miguel Arredondo, Freddy Guevara, Carmen Garrido, Judit Morelló, Sonia Rodríguez‐Nóvoa, Mònica Córdoba, Juan González‐Lahoz, Vincent Soriano   +8 more
openalex   +1 more source

Weight change with antiretroviral switch from integrase inhibitor or tenofovir alafenamide-based to Doravirine-Based regimens in people with HIV

HIV Research & Clinical Practice
Background Weight gain has been well-described with integrase strand transfer inhibitors (INSTIs) and tenofovir alafenamide (TAF). Doravirine (DOR) has been identified as a relatively “weight-neutral” drug; however, there is little data describing its ...
Arianna E. Kousari, Melissa P. Wilson, Kellie L. Hawkins, Mohamed Mehdi Bandali, Andrés F. Henao-Martínez, Edward M. Gardner, Kristine M. Erlandson   +6 more
doaj   +1 more source