Results 171 to 180 of about 38,544 (277)

Chemistry and Structure−Activity Relationship of HIV-1 Integrase Inhibitor Integracide B and Related Natural Products

, 2003
Sheo B. Singh, John G. Ondeyka, William A. Schleif, Peter J. Felock, Daria J. Hazuda   +4 more
openalex   +1 more source

Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential

, 2022
P.J. Slavish, M.G. Cuypers, Mary Ashley Rimmer, Alireza Abdolvahabi, Trushar Jeevan, Gyanendra Kumar, Jamie Jarusiewicz, Sivaraja Vaithiyalingam, Jeremy C. Jones, John J. Bowling, Jeanine E. Price, Rebecca M. DuBois, Jaeki Min, Richard J. Webby, Zoran Ranković, Stephen W. White   +15 more
openalex   +1 more source

Effectiveness and safety of two-drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with HIV: Data from the COMBINE-2 study. [PDF]

HIV Med
Mussini C, Henegar C, Assoumou L, de Wit S, Johnson M, Quiros-Roldan E, Kenyon C, Deschanvres C, Zucman D, Post F, Movahedi R, Comi L, Fox J, Liegeon G, Martin C, Edwards J, Tiecco G, Delforge M, Ragone L, Jones B, van Wyk J, Aboud M, Fletcher C, Pozniak A, Vannappagari V.   +24 more
europepmc   +1 more source

Efavirenz Pharmacogenetics and Weight Gain Following Switch to Integrase Inhibitor-Containing Regimens. [PDF]

Clin Infect Dis, 2021
Leonard MA, Cindi Z, Bradford Y, Bourgi K, Koethe J, Turner M, Norwood J, Woodward B, Erdem H, Basham R, Baker P, Rebeiro PF, Sterling TR, Hulgan T, Daar ES, Gulick R, Riddler SA, Sinxadi P, Ritchie MD, Haas DW.   +19 more
europepmc   +1 more source

Single‐dose pharmacokinetics and safety of ACC017, a novel HIV integrase inhibitor, in healthy adult participants: A first‐in‐human study [PDF]

Chaoying Hu, Y. Li, Yijun Zhou, Dong Zhao, Hui‐Yu Sun, Bin Li, Jing Ji, F. Zhang, Hong Qin, X. Yun   +9 more
openalex   +1 more source

The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors [PDF]

, 2013
Lei Feng, Amit Sharma, Alison Slaughter, Nivedita Jena, Yasuhiro Koh, Nikolozi Shkriabai, Ross C. Larue, Pratiq A. Patel, Hiroaki Mitsuya, Jacques J. Kessl, Alan Engelman, James R. Fuchs, Mamuka Kvaratskhelia   +12 more
openalex   +1 more source

Deep sequencing reveals underestimated burden of integrase inhibitor resistance mutations in people living with HIV: a global individual patient data meta-analysis. [PDF]

Emerg Microbes Infect
Yuan D, Zhao F, Liu Y, Liu S, Yan H, Liu L, Zhang T, Wang B, Su B.   +8 more
europepmc   +1 more source

Integrase Inhibitor Use Associated with Weight Gain in Women and Incident Diabetes Mellitus. [PDF]

AIDS Res Hum Retroviruses, 2022
Asundi A, Olson A, Jiang W, Varshney SP, White LF, Sagar M, Lin NH.   +6 more
europepmc   +1 more source

Emerging role of integrase inhibitors in the management of treatment-experienced patients with HIV infection

, 2009
Christine Katlama
openalex   +2 more sources

Longitudinal analysis of metabolic changes in people with HIV on integrase inhibitor-based versus efavirenz-based therapy: a prospective real-world cohort study in China. [PDF]

BMC Infect Dis
Tao M, Xia M, Yu T, Li B, Peng J, Cai S, Xu X.   +6 more
europepmc   +1 more source