Impact of integrase inhibitors on gut and oral microbiome
Human immunodeficiency virus (HIV) infection is now considered a chronic disease thanks to the extended use of antiretroviral treatment (ART). However, chronic immune activation, inflammation, and increased bacterial translocation (BT) could persist in these patients despite ART.
openaire +3 more sources
Dimerization inhibitors of HIV-1 reverse transcriptase, protease and integrase: A single mode of inhibition for the three HIV enzymes? [PDF]
María‐José Camarasa+4 more
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Discovery of a small-molecule HIV-1 integrase inhibitor-binding site [PDF]
Laith Q. Al‐Mawsawi+6 more
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Congenital malformations and preeclampsia associated with integrase inhibitor use in pregnancy: A single-center analysis. [PDF]
Smith C+12 more
europepmc +1 more source
Novel HIV Integrase Inhibitors with Anti-HIV Activity: Insights into Integrase Inhibition from Docking Studies [PDF]
Arthur G. Cox, Vasu Nair
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Weight and Metabolic Outcomes in Naïve HIV Patients Treated with Integrase Inhibitor-Based Antiretroviral Therapy: A Systematic Review and Meta-Analysis. [PDF]
Valenzuela-Rodriguez G+3 more
europepmc +1 more source
Single amino acid substitution in HIV‐1 integrase catalytic core causes a dramatic shift in inhibitor selectivity [PDF]
Laith Q. Al‐Mawsawi+2 more
openalex +1 more source
Correction for Underwood et al., "Integrase Inhibitor Resistance Mechanisms and Structural Characteristics in Antiretroviral Therapy-Experienced, Integrase Inhibitor-Naive Adults with HIV-1 Infection Treated with Dolutegravir plus Two Nucleoside Reverse Transcriptase Inhibitors in the DAWNING Study". [PDF]
Underwood M+9 more
europepmc +1 more source
Safety and Pharmacokinetics of GSK364735, a Human Immunodeficiency Virus Type 1 Integrase Inhibitor, following Single and Repeated Administration in Healthy Adult Subjects [PDF]
Y. Sunila Reddy+6 more
openalex +1 more source
Increasing trend of transmitted integrase inhibitor resistance in a cohort of antiretroviral therapy-naive people living with HIV. [PDF]
Muccini C+5 more
europepmc +1 more source