Results 151 to 160 of about 16,702 (172)
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Integrase inhibitor gains FDA approval
American Journal of Health-System Pharmacy, 2007Merck on October 12 announced the approval of raltegravir, an HIV integrase inhibitor, as part of a combination regimen in treatment-experienced HIV-infected adults whose virus is active and resistant to multiple antiviral agents.
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[Integrase inhibitor, CCR5 antagonist, fusion inhibitor].
Nihon rinsho. Japanese journal of clinical medicine, 2010Integrase inhibitors have a novel antiretroviral mechanism which prevents proviral DNA integration into the CD4+ cell chromosome. Promising results have been seen in clinical trials in treatment-naïve and -experienced infected individuals. CCR5 antagonists bind to CCR5, one of the second receptors of HIV-1, and inhibit HIV-1 entry into CD4+ cells ...
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[Second-generation integrase inhibitors].
Klinicka mikrobiologie a infekcni lekarstvi, 2018Antiretroviral therapy is the only effective treatment of HIV infection. Based on data demonstrating the beneficial effect of therapy in all HIV patients, the percentage of persons receiving treatment has increased in recent years. HIV integrase inhibitors play an important role in modern therapy.
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HIV Integrase Inhibitors and Entry Inhibitors
2021Daniel Bradshaw, Ranjababu Kulasegaram
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[New CCR5 inhibitor antiretroviral drugs and integrase inhibitors].
Revista clinica espanola, 2009Two new antiretroviral drugs belonging to a new drug family have recently been marketed in Spain. These are maraviroc (CCR5 correceptor inhibitor) and raltegravir (integrase inhibitor). These have the advantage of not presenting crossed resistance with other previously administered antiretroviral drugs, converting them into the cornerstone of the ...
V J, Moreno Cuerda +3 more
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Allosteric Integrase Inhibitors
2016Victoria Hann, Peter Dawson, Mark Ashton
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Can integrase inhibitors reduce mortality?
The Lancet HIV, 2022Marina B, Klein, Jim, Young
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