Results 111 to 120 of about 554,536 (332)

In pursuit of excellence: an integrated care pathway for C1 inhibitor deficiency [PDF]

, 2013
A L Manson, Amy Price, John Dempster, P Clinton-Tarestad, C Greening, R Enti, Sean Hill, Sofia Grigoriadou, Matthew Buckland, Hilary Longhurst   +9 more
openalex   +1 more source

Redefining Workforce Development in Northeast Ohio: How National WorkAdvance Demonstration Made Local Impact [PDF]

, 2016
The Fund for Our Economic Future, Deaconess Foundation and The Raymond John Wean Foundation, along with grantee partner Towards Employment, are pleased to release a local impact report on WorkAdvance, a national pilot tested in Northeast Ohio over the ...

core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Integrated children’s clinic care (ICCC) versus a self-directed care pathway for children with a chronic health condition: a multi-centre randomised controlled trial study protocol [PDF]

, 2018
Thuy Frakking, John Waugh, Hsien-Jin Teoh, Doug Shelton, Susan Moloney, Donna Ward, Michael David, Matthew Barber, Hannah Carter, Sharon Mickan, Kelly A. Weir   +10 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

CARIBOU-1: A pilot controlled trial of an Integrated Care Pathway for the treatment of depression in adolescents. [PDF]

JCPP Adv, 2022
Courtney DB, Cheung A, Henderson J, Bennett K, Wang W, Chen S, Battaglia M, Strauss J, Mitchell R, Wang K, Relihan J, Prebeg M, Darnay K, Szatmari P.   +13 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Developing an integrated depression and tuberculosis care pathway using a co-design approach in a low-resource setting

International Journal of Mental Health Systems
Background Evidence suggests the use of a participatory approach for the improvement of TB care, however, there is limited evidence on how integrated depression screening and care could be delivered with TB services.
Olamide Todowede, Zara Nisar, Saima Afaq, Sushama Kanan, Aliya Ayub, Rumana Huque, Akhtar Hussain, Mudasser Shehzad, Najma Siddiqi   +8 more
doaj   +1 more source

A Novel Approach to Delivering Evidence-based, High-quality Care in Psychiatry Through an Electronic Integrated Care Pathway (eICP) Pilot. [PDF]

Psychiatr Q, 2023
Li L, Kruger M, Kim N, Ong S, Riley S, Cameron K, Koslosky K, Rhodes D.   +7 more
europepmc   +1 more source

Patients’ experiences and care needs during the diagnostic phase of an integrated brain cancer pathway: A case study [PDF]

, 2018
Tina Wang Vedelø, Jens Christian Hedemann Sørensen, Charlotte Delmar   +2 more
openalex   +1 more source