Results 81 to 90 of about 436,807 (278)
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
Advanced Science, EarlyView.This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber +12 more
wiley +1 more source
Automation of closed environments in space for human comfort and safety [PDF]
The development of Environmental Control and Life Support Systems (ECLSS) for Space Station Freedom, future colonization of the Moon, and Mars missions presents new challenges for present technologies.
core +1 more source
Semantic reasoning for intelligent emergency response applications [PDF]
, 2013 Emergency response applications require the processing of large amounts of data, generated by a diverse set of sensors and devices, in order to provide for an accurate and concise view of the situation at hand.
De Turck, Filip +2 more
core +2 more sources
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
Journal of Combustion, 2011 Wildland fire risk assessment and fuel management planning on federal lands in the US are complex problems that require state-of-the-art fire behavior modeling and intensive geospatial analyses. Fuel management is a particularly complicated process where
Alan A. Ager +2 more
doaj +1 more source
Training of Crisis Mappers and Map Production from Multi-sensor Data: Vernazza Case Study (Cinque Terre National Park, Italy) [PDF]
, 2012 This aim of paper is to presents the development of a multidisciplinary project carried out by the cooperation between Politecnico di Torino and ITHACA (Information Technology for Humanitarian Assistance, Cooperation and Action).
Boccardo, Piero +7 more
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Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
Advanced Science, EarlyView.ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source
A feasibility study: Forest Fire Advanced System Technology (FFAST) [PDF]
The National Aeronautics and Space Administration/Jet Propulsion Laboratory and the United States Department of Agriculture Forest Service completed a feasibility study that examined the potential uses of advanced technology in forest fires mapping and ...
Martin, T. Z., Mcleod, R. G., Warren, J.
core +1 more source
Distributed agent-based building evacuation simulator [PDF]
, 2012 The optimisation of the evacuation of a building plays a fundamental role in emergency situations. The behaviour of individuals, the directions that civilians receive, and the actions of the emergency personnel, will affect the success of the operation ...
Filippoupolitis, Avgoustinos +6 more
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