Results 121 to 130 of about 298,958 (272)

Phi fluctuates with surprisal: An empirical pre-study for the synthesis of the free energy principle and integrated information theory. [PDF]

PLoS Comput Biol, 2023
Lundbak Olesen C, Waade PT, Albantakis L, Mathys C.   +3 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Is Consciousness Computable? Quantifying Integrated Information Using Algorithmic Information Theory [PDF]

, 2014
In this article we review Tononi’s (2008) theory of consciousness as integrated information. We argue that previous formalizations of integrated information (e.g. Griffith, 2014) depend on information loss.
Maguire, Phil, Griffith, Virgil, Maguire, Rebecca, Moser, Philippe   +3 more
core  

An adversarial collaboration protocol for testing contrasting predictions of global neuronal workspace and integrated information theory. [PDF]

PLoS One, 2023
Melloni L, Mudrik L, Pitts M, Bendtz K, Ferrante O, Gorska U, Hirschhorn R, Khalaf A, Kozma C, Lepauvre A, Liu L, Mazumder D, Richter D, Zhou H, Blumenfeld H, Boly M, Chalmers DJ, Devore S, Fallon F, de Lange FP, Jensen O, Kreiman G, Luo H, Panagiotaropoulos TI, Dehaene S, Koch C, Tononi G.   +26 more
europepmc   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

The ambiguous feeling between "mine" and "not-mine" measured by integrated information theory during rubber hand illusion. [PDF]

Sci Rep, 2022
Niizato T, Nishiyama Y, Sakamoto K, Kazama T, Okabayashi T, Yamaguchi T.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Does integrated information theory make testable predictions about the role of silent neurons in consciousness? [PDF]

Neurosci Conscious, 2022
Bartlett G.
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Towards an integrated model of information behavior

, 2008
Information behavior models generally focus on one of many aspects of information behavior, either information finding, conceptualized as information seeking, information foraging or information sense-making, information organizing and information using.
Narayan, Bhuva, Spink, Amanda H.
core