Results 41 to 50 of about 1,016,597 (325)

Protocols for Scholarly Communication [PDF]

open access: yes, 2006
CERN, the European Organization for Nuclear Research, has operated an institutional preprint repository for more than 10 years. The repository contains over 850,000 records of which more than 450,000 are full-text OA preprints, mostly in the field of ...
Pepe, Alberto, Yeomans, Joanne
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Panoràmica dels sistemes de gestió de biblioteques al segle XXI

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2005
En la darrera dècada s’han consolidat un conjunt de tendències en l’àmbit de la informàtica general que han afectat profundament les biblioteques. La popularització d’Internet, l’aparició de sistemes oberts i interoperables, la consolidació d’entorns ...
Salse i Rovira, Marina
doaj  

The development of environmental management systems and corporate responsibility reporting in NZ, UK and USA : a thesis presented in partial fulfilment of the requirements for the degree of Master of Environmental Management at Massey University, New Zealand [PDF]

open access: yes, 2017
L. C. Martinez. The Development of Environmental Management Systems and Corporate Responsibility Reporting in NZ, UK and USA, 121 pages, 2 figures, 2017.
Martinez, Lucy
core  

Assessing digital preservation frameworks: the approach of the SHAMAN project [PDF]

open access: yes, 2009
How can we deliver infrastructure capable of supporting the preservation of digital objects, as well as the services that can be applied to those digital objects, in ways that future unknown systems will understand?
Elena, M.   +5 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

RDA and library systems

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2007
L'article planteja el rerefons del desenvolupament de l'RDA (descripció i accés a recursos), un estàndard de metadades de caràcter internacional adreçat a un ample ventall de comunitats de metadades.
Dunsire, Gordon
doaj  

Librarians’ Perceptions About Adoption and Uses of The Integrated Library Software

open access: yesIndonesian Journal of Educational Research and Technology
The main objective of this study was to investigate the factors that influenced the adoption of Koha-integrated library software by librarians in Sri Lankan universities and libraries and to examine the challenges that were encountered during the ...
N. G.D.A. Jayarathna, H. M.M.N. Herath
doaj   +1 more source

Developing an Electronic Resource Management System: Verde from Ex Libris

open access: yesLiber Quarterly: The Journal of European Research Libraries, 2004
Rapid growth in the number of electronic resources and the complexity of managing e-collections has posed new challenges for libraries and hence requires the development of new tools.
Tamar Sadeh
doaj   +1 more source

Modelling methods for determining fault management requirements in future MEA and MEE platforms [PDF]

open access: yes, 2017
This paper presents a modular transient modelling tool which provides model-based support for the design and technology selection within future MEE and MEA electrical systems.
Burt, G. M.   +4 more
core  

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