Results 101 to 110 of about 311,065 (292)

Reliable Integrated Photonic Light Sources Using Curved Al2O3:Er3+ Distributed Feedback Lasers

open access: yesIEEE Photonics Journal, 2017
We propose a curved erbium doped aluminum oxide (Al2O3:Er3+) distributed feedback (DFB) laser for a reliable integrated photonics light source. The curved structure allows us for compensation of the radially varying film thickness due to the Al2O3:
Nanxi Li   +8 more
doaj   +1 more source

An investigation for the development of an integrated optical data preprocessor [PDF]

open access: yes
The successful fabrication and demonstration of an integrated optical circuit designed to perform a parallel processing operation by utilizing holographic subtraction to simultaneously compare N analog signal voltages with N predetermined reference ...
Chapman, C. M.   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Focus on integrated quantum optics

open access: yesNew Journal of Physics, 2013
A key goal of research into quantum information processing is the development of technologies that are scaleable in complexity while allowing the mass manufacture of devices that promise transformative effects on information science.
Jeremy O'Brien   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Ultra-Compact Mach–Zehnder Refractometer Based on Rice-Shaped Air Cavity Beam Expansion

open access: yesPhotonics
This paper reports and demonstrates, for the first time, a Mach–Zehnder interferometer (MZI) sensor for refractive index (RI) detection based on a rice-shaped air cavity (RAC).
Zonghao Mu   +4 more
doaj   +1 more source

Characterisation of fabrication inhomogeneities in Ti:LiNbO3 waveguides

open access: yesNew Journal of Physics, 2019
Nonlinear processes in integrated, guiding systems are fundamental for both classical and quantum experiments. Integrated components allow for compact, modular and stable light-processing systems and as such their use in real-world systems continues to ...
Matteo Santandrea   +3 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

From quantum pulse gate to quantum pulse shaper -- enigneered frequency conversion in nonlinear optical waveguides

open access: yes, 2011
Full control over the spatio-temporal structure of quantum states of light is an important goal in quantum optics, to generate for instance single-mode quantum pulses or to encode information on multiple modes, enhancing channel capacities. Quantum light
Andreas Christ   +10 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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