Results 101 to 110 of about 3,008,385 (305)

Terahertz resonant transmission through metallic mesh truss structures

open access: yesAIP Advances, 2019
In mechanical engineering, truss structures have attracted much attention because of their mechanical strength and light weight. However, electromagnetic properties of truss structures have been rarely reported.
Chul Kang   +6 more
doaj   +1 more source

Reliable Integrated Photonic Light Sources Using Curved Al2O3:Er3+ Distributed Feedback Lasers

open access: yesIEEE Photonics Journal, 2017
We propose a curved erbium doped aluminum oxide (Al2O3:Er3+) distributed feedback (DFB) laser for a reliable integrated photonics light source. The curved structure allows us for compensation of the radially varying film thickness due to the Al2O3:
Nanxi Li   +8 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Linear Integrated Optics in 3C Silicon Carbide

open access: yes
Dataset for the paper Linear Integrated Optics in 3C Silicon ...
Politi, Alberto, Martini, Francesco
core   +1 more source

Long-wavelength III-V/silicon photonic integrated circuits [PDF]

open access: yes, 2013
We review our work in the field of short-wave infrared and mid-infrared photonic integrated circuits for applications in spectroscopic sensing systems.
Hu, ChenUGent0001109237428020011223079729429146250000-0002-1442-29983BAA5E3A-F0EE-11E1-A9DE-61C894A0A6B4   +85 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Optical pulse generation using fiber lasers and integrated optics [PDF]

open access: yes, 1995
We have demonstrated an optical pulse forming system using fiber and integrated optics, and have designed a multiple-output system for a proposed fusion laser facility.
Browning, D. F.   +3 more
core  

Characterisation of fabrication inhomogeneities in Ti:LiNbO3 waveguides

open access: yesNew Journal of Physics, 2019
Nonlinear processes in integrated, guiding systems are fundamental for both classical and quantum experiments. Integrated components allow for compact, modular and stable light-processing systems and as such their use in real-world systems continues to ...
Matteo Santandrea   +3 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

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