Results 81 to 90 of about 15,696 (258)
High Sensitive Directional Twist Sensor Based on a Mach–Zehnder Interferometer
IEEE Photonics Journal, 2018 A new type of Mach–Zehnder interferometer (MZI) is proposed to measure twist and temperature. The sensor contains a pretwisted taper and a ball. The pretwisted taper is made by pretwisted, and then, thermally tapering along a single-mode fiber, to
Shujie Duan +11 more
doaj +1 more source
Watt-Level Continuous-Wave Mode-Locked Nd:YVO4 Laser With ReSe2 Saturable Absorber
IEEE Photonics Journal, 2020 We report a ReSe2 passively mode-locked composite YVO4/Nd:YVO4 laser at 1.06 μm, which can stably generate pure continuous-wave mode-locking (CWML) operation at watt-level output. ReSe2, as a new type of 2-D transition metal dichalcogenides
Yuchen Xue +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Synthetic holographic beamsplitters for integrated optics
, 1991 We propose the application of computer-generated Fourier domain holograms to wavefront synthesis and manipulation in integrated optics. In particular, we describe the use of such diffractive optical elements to split a guided plane wave into several ...
Salin, Arto U. +5 more
core +1 more source
Double-sided fresnel zone plates as high performance optics in X-ray microscopy [PDF]
, 2015 X-ray microscopy describes a range of analytical techniques, specialized for the characterization of organic and inorganic samples using high energy photons.
Mohácsi, István
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Integrated microlenses and multimode interference devices for microflow cytometers
, 2010 The convergence of microfabrication technologies, novel materials systems, and techniques for chemical and biochemical analysis is enabling the realisation of lab-on-a-chip technology.
Hunt, Hamish C, Hunt, Hamish C.
core
MEMS-based incandescent microlamps for integrated optics applications
, 2008 In this work we present the fabrication and operation of incandescent microlamps for integrated optics applications. This microlamp emits white and infrared light from a chromium resistor embedded in a free-standing silicon oxynitride (SiO(x)N(y ...
Chávez, Marco Isaías Alayo +2 more
core +1 more source
Integrated-optics-based external-cavity laser configured for mode-hop-free wavelength tuning [PDF]
, 2022 Aspects of the present disclosure describe systems, methods and structures including an integrated-optics-based externa-cavity laser configured for mode-hop-free wavelength tuning having an increased continuous tuning range with an ultra-narrow linewidth
Oldenbeuving, Ruud M. +4 more
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source