FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Electrochemical protein biosensors for disease marker detection: progress and opportunities
Microsystems & NanoengineeringThe development of artificial intelligence-enabled medical health care has created both opportunities and challenges for next-generation biosensor technology. Proteins are extensively used as biological macromolecular markers in disease diagnosis and the
Lanpeng Guo +7 more
doaj +1 more source
Metamaterial Waveguide Devices for Integrated Optics. [PDF]
Materials (Basel), 2017 Amemiya T +3 more
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Tunable Multifunctional Terahertz Coding Metasurface for Polarization Manipulation
Advanced Photonics ResearchCoding metasurfaces (CMs) exhibit powerful capabilities in manipulating electromagnetic waves. Although conventional CMs are capable of manipulating both linearly polarized (LP) and circularly polarized (CP) waves, the Pancharatnam–Berry phase methods ...
Chunsheng Zhang +10 more
doaj +1 more source
Design of an Integrated Optics Sensor Structure Based on Diamond Waveguide for Hemoglobin Property Detection. [PDF]
Materials (Basel), 2019 Struk P.
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Harnessing temporal modes for multi-photon quantum information processing based on integrated optics. [PDF]
Philos Trans A Math Phys Eng Sci, 2017 Harder G +4 more
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Rotating Circular Micro-Platform with Integrated Waveguides and Latching Arm for Reconfigurable Integrated Optics. [PDF]
Micromachines (Basel), 2017 Briere J +7 more
europepmc +1 more source