Results 211 to 220 of about 1,325,823 (331)

Hot gas cleanup using solid supported molten salt for integrated coal gasification/molten carbonate fuel cell power plants. Topical report, October 1982-December 1983

, 1983
Lyke, Sealock, Roberts
openalex   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Estimating abundance of harvested populations at the management unit scale. [PDF]

PLoS One
Keever AC, Kelly JD, Clevinger GB, Cohen BS.   +3 more
europepmc   +1 more source

Integrated passive-solar demonstration project. Final report

, 1982
M. Garrison
openalex   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Criteria for designing integrated diagnosis interventions in low resource settings at the primary care level: a Delphi consensus study. [PDF]

BMC Health Serv Res
Gwaza GP, Plüddemann A, MacBain McCall M, Dittrich S, Heneghan C.   +4 more
europepmc   +1 more source

Proof of concept testing of an integrated dry injection system for SO{sub x}/NO{sub x} control. Quarterly technical progress report, April--June, 1989

, 1989
D.J. Helfritch, S.J. Bortz, R. Beittel
openalex   +2 more sources

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Development and testing of an integrated signal validation system for nuclear power plants. Final Report, Volume 2

, 1989
B. R. Upadhayaya, T.W. Kerlin, Keith E. Holbert, O. Glöckler, V.M. Morgenstern, Z. Frei, J. Olvera, P.J. Gaudio   +7 more
openalex   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source