Results 241 to 250 of about 1,325,823 (331)

SensRORing cholesterol to drive protumoral myelopoiesis

Molecular Oncology, EarlyView.
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley   +1 more source

Implementing CYP2C19-guided clopidogrel therapy: a scoping review of pharmacogenomic testing services. [PDF]

Pharmacogenomics J
Patel TJ, Wehbe E, Hughes S, Patanwala AE, Kritharides L, Lal S, Patel S, Stocker SL.   +7 more
europepmc   +1 more source

Synthesis of an integrated mechanism by a computer-aided method. 2nd Report. Dimensions of space and the freedom of mechanism.

, 1990
Motozou IHARA, Osamu Suenaga, Xiaojun ZHAO, T. Nogai   +3 more
openalex   +2 more sources

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Exploring the Current Practices of Universities Regarding the Risk of Violence Towards Undergraduate Students on Clinical Placements: A Scoping Review. [PDF]

Health Serv Insights
Jacob A, Spelten E, Kinsman L.
europepmc   +1 more source

Integrated methods for production of clean char and its combustion properties. Quarterly technical report, December 1, 1992--February 28, 1993

, 1993
J.A. DeBarr, Massoud Rostam‐Abadi, Brian K. Gullett, Steven A. Benson, D.L. Toman, F.I. Honea   +5 more
openalex   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Analyzing organic sulfur in coal/char: Integrated mild degradation/XANES methods. [Quarterly] technical report, September 1--November 30, 1993

, 1993
Stuart Palmer, G.P. Huffman
openalex   +2 more sources

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source