Results 51 to 60 of about 44,724 (245)

Flexible Recipe Method and Decomposition Algorithm for Integrating Production Operations and Dynamic Optimization of Continuous Manufacturing Processes

Chemical Engineering Transactions, 2015
For the continuous manufacturing processes, the integrated optimization for production planning, scheduling, and dynamic optimization usually leads to profit improvement and better overall performance. The challenge is that the integrated optimization is
H. Shi, F. You
doaj   +1 more source

Robust Optimal Scheduling of Integrated Energy Systems Considering the Uncertainty of Power Supply and Load in the Power Market

Energies, 2023
The integrated energy system is a complex energy system that involves multi-stakeholder and multi-energy coordinated operations. The key to improving its scale and sustainable development is to construct a better-integrated energy system dispatching ...
Lang Zhao, Yuan Zeng, Zhidong Wang, Yizheng Li, Dong Peng, Yao Wang, Xueying Wang   +6 more
doaj   +1 more source

Integrating Nurse and Surgery Scheduling [PDF]

SSRN Electronic Journal, 2006
One common problem at hospitals is the extreme variation in daily (even hourly) workload pressure for nurses. The operating room is considered to be the main engine and hence the main generator of variance in the hospital. It is our believe that integrating the operation room scheduling process with the nurse scheduling process is a simple, yet ...
Jeroen Belien, Erik Demeulemeester
openaire   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

Integrated Production and Transportation Scheduling Method in Hybrid Flow Shop

Chinese Journal of Mechanical Engineering, 2022
The connection between production scheduling and transportation scheduling is getting closer in smart manufacturing system, and both of those problems are summarized as NP-hard problems.
Wangming Li, Dong Han, Liang Gao, Xinyu Li, Yang Li   +4 more
doaj   +1 more source

Integral Approaches to Integrated Scheduling

, 2007
In this chapter we have tried to address some integrative views for the production scheduling problem; namely resources integration, cost elements integration and solution methodologies integration. Representative literature was also covered. The integrative views oriented our attention to the necessity of having a diagnosis methodology assessing the ...
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source