Results 41 to 50 of about 68,699 (269)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Fast Tunable Biological Fluorescence Detection Device with Integrable Liquid Crystal Filter

Crystals, 2021
Detecting a variety of biological samples accurately and swiftly in an integrated way is of great practical significance. Currently, biofluorescent spectrum detection still largely relies on microscopic spectrometers.
Qing Yang, Tong Sun, Xinyu Wu, Guangchao Cui, Mengzheng Yang, Zhongyang Bai, Lin Wang, Helin Li, Wenjing Chen, Qunwen Leng, Robert Puers, Ceyssens Frederik, Michael Kraft, Qinglin Song, Huabin Fang, Dewen Tian, Dexin Wang, Huijie Zhao, Weisheng Zhao, Tianxiao Nie, Qi Guo, Lianggong Wen   +21 more
doaj   +1 more source

A survey of volatile species in Oort cloud comets C/2001 Q4 (NEAT) and C/2002 T7 (LINEAR) at millimeter wavelengths [PDF]

, 2013
The line emission in the coma was measured in the comets C/2001 Q4 (NEAT) and C/2002 T7 (LINEAR), that were observed on five consecutive nights, 7-11 May 2004, at heliocentric distances of 1.0 and 0.7 AU, respectively, by means of high-resolution ...
Biver, N., Bockelée-Morvan, D., Crovisier, J., de Val-Borro, M., Hartogh, P., Jarchow, C., Küppers, M., Rezac, L., Villanueva, G. L.   +8 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Integrated High-resolution Photonic Spectrometer

Proceedings of The 7th International Multidisciplinary Conference on Optofluidics 2017, 2017
An integrated high-resolution on-chip spectrometer is designed, fabricated and experimentally tested. A thermally tunable microring resonator is adopted to function as a tunable filter so as to retrieve the input spectrum. The robust integrated spectrometer is quite compact, low cost and CMOS-compatible.
Aiqun Liu, Shaonan Zheng, Hong Cai, Yuandong Gu   +3 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Miniaturized Continuous-Wave Terahertz Spectrometer With 3.6 THz Bandwidth Enabled by Photonic Integration and Microelectronics

IEEE Access
Broadband terahertz spectroscopy is a valuable analytical tool in science and a promising technology for industrial non-destructive, non-contact testing, e.g. thickness measurements of thin dielectric layers.
Simon Nellen, Lauri Schwenson, Lars Liebermeister, Milan Deumer, Sebastian Lauck, Martin Schell, Robert B. Kohlhaas   +6 more
doaj   +1 more source

A Multidisciplinary Approach to High Throughput Nuclear Magnetic Resonance Spectroscopy

Sensors, 2016
Nuclear Magnetic Resonance (NMR) is a non-contact, powerful structure-elucidation technique for biochemical analysis. NMR spectroscopy is used extensively in a variety of life science applications including drug discovery.
Hossein Pourmodheji, Ebrahim Ghafar-Zadeh, Sebastian Magierowski   +2 more
doaj   +1 more source

High-resolution wide-band Fast Fourier Transform spectrometers

, 2012
We describe the performance of our latest generations of sensitive wide-band high-resolution digital Fast Fourier Transform Spectrometer (FFTS). Their design, optimized for a wide range of radio astronomical applications, is presented.
A. Bell, B. Klein, Benz, Carter, Heyminck, I. Krämer, K. Meyer, Klein, R. Güsten, S. Hochgürtel, Stanko, Weinreb   +11 more
core   +1 more source

PR21 Integrated Photonic Spectrometer STTR_16

, 2022
The goal of this project was to design silicon photonic components for a microchip-scale spectrometer. Future earth science and space missions may benefit from spectroscopic measurements made using compact, energy efficient and inexpensive instruments.
openaire   +2 more sources