Results 41 to 50 of about 14,546 (292)

Integrated Spectrometers on Silicon Photonics Platform [PDF]

open access: yes, 2021
Spectrally resolved interferometry is used in biosensing and bioimaging and has the advantages of high sensitivity and label free sensing. Spectrally resolved interferometry also has application in spectral domain optical coherence tomography (SD-OCT ...

core  

Dual Tunable MZIs Stationary-Wave Integrated Fourier Transform Spectrum Detection

open access: yesSensors, 2021
In order to resolve spectral alias due to under sampling in traditional stationary-wave integrated Fourier transform (SWIFT) spectrometers, an all-on-chip waveguide based on dual tunable Mach-Zehnder interferometer (MZI) stationary-wave integrated ...
Xinyang Chen   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Integrated spectrometer design with application to multiphoton microscopy

open access: yesOptics Express, 2010
We present a prism-based spectrometer integrated into a multifocal, multiphoton microscope. The multifocal configuration facilitates interrogation of samples under different excitation conditions. Notably, the image plane of the microscope and the image plane of the spectrometer are coincident eliminating the need for an intermediate image plane ...
Eric V, Chandler   +2 more
openaire   +2 more sources

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Miniaturized Continuous-Wave Terahertz Spectrometer With 3.6 THz Bandwidth Enabled by Photonic Integration and Microelectronics

open access: yesIEEE Access
Broadband terahertz spectroscopy is a valuable analytical tool in science and a promising technology for industrial non-destructive, non-contact testing, e.g. thickness measurements of thin dielectric layers.
Simon Nellen   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Fast Tunable Biological Fluorescence Detection Device with Integrable Liquid Crystal Filter

open access: yesCrystals, 2021
Detecting a variety of biological samples accurately and swiftly in an integrated way is of great practical significance. Currently, biofluorescent spectrum detection still largely relies on microscopic spectrometers.
Qing Yang   +21 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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