Results 111 to 120 of about 389,974 (269)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Integrated Management Systems in Latvian Enterprises
Standards in different areas - quality, environment, occupational health and safety - are tools for deployment of sustainable development in any enterprise regardless of its size or sector of industry.
Mazais, Jānis, Mežinska, Iveta
core
, 2018 Biogas and anaerobic digestion can positively contribute to several Sustainable Development Goals (SDGs). This report produced by IEA Bioenergy Task 37, addresses local applications of integrated biogas concepts.
Schmidt, Thomas, McCabe, Bernadette K.
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Integrated Design-to-Control Approach for Holonic Manufacturing Systems
, 2001 Next generation manufacturing systems will be integrated networks of distributed resources simultaneously capable of combined knowledge and material processing. These manufacturing systems will be required to be agile, flexible, and fault-tolerant.
Wang, Lihui,
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Scientific ReportsSynthetic antiferromagnetic (AF) pinned layers are widely used in order to reduce the stray field of the pinned layer and stabilize the magnetic alignment of the reference layer in perpendicular magnetic tunnel junctions (MTJs). Here, a detailed study of
Yoshiaki Saito +6 more
doaj +1 more source
Managing the Hydra in integration: developing an integrated assessment tool for agricultural systems
, 2009 Keywords: modelling, bio-economic, farm, simulation, ontology, knowledge management, Europe, agricultural management, database, scenario Ex-ante assessment through science-based methods can provide insight into the impacts of potential policy measures ...
Janssen, S.J.C.
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source