Results 231 to 240 of about 134,683 (295)

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

A modular clinical thinking navigation system: an exploration in the '101 Project' diagnostics textbook reform. [PDF]

BMC Med Educ
Bi R, Zhang Y, Jiang R, Jin T, Yang J, Song L, Zhou J, Zhang H, Ye T, Zhou X, Zhan H.   +10 more
europepmc   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

AI and the transformation of clinical reasoning: A classroom perspective. [PDF]

PLOS Digit Health
Nguyen NP.
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

An embodied cognition based model of medical experts' tacit knowledge: structure, hierarchies, and transformation. [PDF]

Front Digit Health
Zhou H, Chang X, Zhou X, Shi J, Zhou Z, Zhong S.   +5 more
europepmc   +1 more source

Application of the combined PBL-CBL teaching method of anaphylactic shock prevention and care in the fundamental nursing course. [PDF]

BMC Med Educ
Jiang X, Hui Y, Tong C, Li D, Zhang C, Chang Y.   +5 more
europepmc   +1 more source

The effect of artificial intelligence-supported applications on critical thinking motivation and clinical decision making in nursing students: path analysis. [PDF]

BMC Med Educ
Özdemir S, Akçoban S, Berşe S, Tosun B.   +3 more
europepmc   +1 more source

Evaluation of the implementation of the One Health approach in Guinea: Application of the NEOH framework to decentralized One Health platforms. [PDF]

One Health
Bongono EF, Hounmenou CG, Maltais S, Mbaye A, Koniono GL, Bangoura ST, Yambayamba M, Diaby M, Keita AK, Touré A, Camara A, Sidimé Y, Rüegg S.   +12 more
europepmc   +1 more source