Results 51 to 60 of about 35,067 (308)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A novel output transformer based highly linear RF-DAC architecture [PDF]

open access: yes, 2013
A major limitation of the linearity of Current Steering (CS) RF-DACs is the large output voltage swing (typically 1Vpp), which couples to sensitive internal nodes and thereby causes non-linear distortion.
Briaire, J.   +9 more
core   +1 more source

Single-Stage Single-Switch curved air gap PFC integrated flyback transformer design

open access: yes, 2023
This paper introduces a novel design for a power factor correction (PFC) integrated flyback transformer, which aims to enhance line harmonic current and common-mode noise reduction. The design includes two stages, a PFC stage with two boost inductors and
Mo, Wai Keung; id_orcid   +2 more
core   +1 more source

Model transformations and tool integration [PDF]

open access: yesSoftware & Systems Modeling, 2005
Model transformations are increasingly recognised as being of significant importance to many areas of software development and integration. Recent attention on model transformations has particularly focused on the OMGs Queries/Views/Transformations (QVT) Request for Proposals (RFP).
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Integration of Silicon-Carbide Schottky Diodes with High-Frequency Transformer

open access: yes, 2022
This paper presents a novel and compact structure of integrated silicon-carbide (SiC) Schottky diodes with highfrequency (HF) transformer. A prototype HF transformer in the shape that is similar to a tokamak is designed for the integration with SiC ...
Yao, Weichong   +5 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Integral Transform of N.I. Akhiezer [PDF]

open access: yes, 2020
We study the integral transform which appeared in a different form in Akhiezer's textbook "Lectures on Integral Transforms".
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Integrating an agent-based wireless sensor network within an existing multi-agent condition monitoring system

open access: yes, 2009
The use of wireless sensor networks for condition monitoring is gaining ground across all sectors of industry, and while their use for power engineering applications has yet been limited, they represent a viable platform for next-generation substation ...
Catterson, V.M.   +5 more
core   +1 more source

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