Results 61 to 70 of about 430,197 (267)

Providing operating modes for Coriolis vibration gyroscopes with low-Q resonators

open access: yesНаучно-технический вестник информационных технологий, механики и оптики
Coriolis vibration gyroscopes are a class of promising inertial primary information sensors that respond to the rotation of the resonator base through Coriolis inertial forces arising in the vibrating shell.
V. V. Matveev   +5 more
doaj   +1 more source

The National, Civic, and Ethnic Identity of Russian Young People in the Republic of Sakha (Yakutia): Perception Dynamics

open access: yesСоциологическая наука и социальная практика, 2019
This paper studies the levels and nature of the national, civic, and ethnic identity of Russian young people in the Republic of Sakha (Yakutia). We analyze identity dynamics and nature, using representative data from large-scale surveys conducted in 2012
Ekaterina M. Arutyunova
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Integrating Signaling Pathways with Transcription Factor Networks—On the Trail of Sisyphus?

open access: yesBiomolecules
In the context of health and disease research, cells use signaling pathways that transduce stimuli from the extracellular environment to modulate intracellular gene expression via the activity of transcription factors and cofactors (coactivators and/or ...
Kostas A. Papavassiliou   +1 more
doaj   +1 more source

Integral polytopes and polynomial factorization

open access: yesTurkish Journal of Mathematics, 2013
For any field F, there is a relation between the factorization of a polynomial f \in F[x1,...,xn] and the integral decomposition of the Newton polytope of f. We extended this result to polynomial rings R[x1,...,xn] where R is any ring containing some elements which are not zero-divisors.
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Polynomial Inverse Integrating Factors, First Integral and Non-Existence of Limit Cycles in the Plane for Quadratic Systems

open access: yesScience Journal of University of Zakho, 2017
The main purpose of this paper is to study the existence of polynomial inverse integrating factor and first integral, and non-existence of limit cycles for all systems. Furthermore, we consider some applications.
Ahmed M. Hussien
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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