Results 91 to 100 of about 8,918,506 (303)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Applying concepts of fuzzy cognitive mapping to model IT/IS investment evaluation factors [PDF]
The justification process is a major concern for many organisations that are considering the adoption of Information Technology (IT) and Information Systems (IS), and is a barrier to its implementation.
Sharif, AM +3 more
core +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Integrating regional transportation and ecological factors into anaerobic digestion siting decisions
Landfilling wasted food (WF) is a significant source of greenhouse gas emissions. Anaerobic digestion (AD) is emerging as a promising alternative to jointly manage WF and generate bio-based energy, yet its widespread adoption is limited by transportation
William R. Armington +4 more
doaj +1 more source
Factorization in integral domains
Les AA. appellent ``atomique'' un anneau intègre R dans lequel tout élément est produit fini des éléments irréducibles. Sont étudiés les anneaux atomiques et les anneaux intègres avec la condition maximale pour les idéaux principaux, les anneaux atomique dans lesquels pour tout élément x non nul et non inversible il existe N(x) tel que pour toute ...
Anderson, D.D. +2 more
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Integrating accompanying patients into clinical oncology teams: limiting and facilitating factors
Objectives Since 2018, four establishments in Quebec have been instrumental in implementing the PAROLE-Onco program, which introduced accompanying patients (APs) into healthcare teams to improve cancer patients’ experience.
Marie-Pascale Pomey +24 more
doaj +1 more source
Global climate change and human activities have increased the frequency of wildfires, posing significant threats to ecosystems and human safety, including in regions traditionally less prone to wildfires.
Luanjie Chen +2 more
doaj +1 more source
Integrating regional and global security cooperation
Inhaltsverzeichnis: Klaus Lange, Leonid L. Fituni: Introduction (5-6); Victor I. Danilov-Danilyan, Valeri G. Draganov, et al.: Opening comments at the conference 'Integrating Regional and Global Security Cooperation', Moscow, 5-6 December 2000 (7-10). I.
Hanns-Seidel-Stiftung e.V. Akademie fuer Politik und Zeitgeschehen, Muenchen (Germany) +2 more
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